Ph.D., Biomedical Engineering, Stony Brook University
M.S., Biomedical Engineering, Stony Brook University
B.E., Biomedical Engineering, Stony Brook University

Areas of Interest

Tissue Engineering of Blood Vessels
Biofluid Flow within the Microcirculation and Macrocirculation
Platelet Activation Potentials
Coagulation Cascade
Nanofabrication
Two-phase, Multi-scale Modeling

Honors and Awards

Award for Academic Excellence in Biomedical Engineering -- Class of 2004
Provosts Award for Academic Excellence -- State University of New York at Stony Brook
Barry M. Goldwater Scholar

Memberships

American Association for the Advancement of Science
Biomedical Engineering Society, BMES
Microcirculation Society
Sigma Xi Research Honor Society

Recent Publications

Bioassay chamber for angiogenesis with perfused explanted arteries and electrospun scaffolding. David Rubenstein, Dong Han, Sara Goldgraben, Hebah El-Gendi, Pelagia-Irene Gouma, Mary D Frame. Microcirculation 2007:14, 723-737.
 
Platelet factor V supports hemostasis in a patient with an acquired factor V inhibitor, as shown by prothrombinase and tenase assays. Maria T. Grosse Perdekamp, MD, David A. Rubenstein, Jolyon Jesty, PhD, Mae B. Hultin, MD. Blood Coagulation & Fibrinolysis 2006; Vol. 17, Issue October: 593-597.
 
Activation of platelets exposed to shear stress in the presence of smoke extracts of low-nicotine and zero-nicotine cigarettes: the protective effect of nicotine. Jaimohan Ramachandran, David Rubenstein, Danny Bluestein, Jolyon Jesty. Nicotine and Tobacco Research. 2004; Vol. 6, No 5, Issue October: 835-841.
 
A shear-restricted pathway of platelet procoagulant activity is regulated by IQGAP1. Wadie Bahou, Lesley Scudder, David Rubenstein, Jolyon Jesty. Journal of Biological Chemistry. 2004; Vol. 279, No 21, Issue May 21: 22571-22577.
 
Differences between mainstream and sidestream cigarette smoke extracts and nicotine in the activation of platelets under static and flow conditions. David Rubenstein; Jolyon Jesty, Danny Bluestein. Circulation. 2004; 109: 78-83.
 
Dose effect of shear stress on platelet complement activation in a dynamic cone and plate shearing device. Wei Yin & David A. Rubenstein. Cellular & Molecular Bioengineering. (in press, available online 3/14/09).
 
The extent of albumin glycation modulates platelet susceptibility to flow induced activation and aggregation. David A. Rubenstein & Wei Yin. Platelets (in press).
 
Biocompatibility of polyureananoencapsulated templated silica aerogel. Wei Yin, Subramanian M. Venkitachalam, Ellen Jarret, Sarah Staggs, Nicholas Leventis, Hongbing Lu, & David A. Rubenstein. Journal of Biomedical Materials Research: Part A (in press).
 
Shear Stress and shear exposure duration regulate flow induced platelet activation and aggregation. David Rubenstein & Wei Yin. Annals of Biomedical Engineering (under review).

Reviewer For

Microcirculation
Annals of Biomedical Engineering
Nicotine and Tobacco Research
Journal of Heat Transfer
Journal of Thrombosis and Haemostasis
Thrombosis Research
National Science Foundation - BME Panel
American Heart Association - Vascular Wall Biology Panel