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Academic Background

Ph.D., Biomedical Engineering, State University of New York at Stony Brook, 2004.
M.S., Biomedical Engineering, The University of Akron, 2001.
B.E., Biomedical Engineering, Tianjin University, China, 1999.
B.A., English, Tianjin University, China, 1999.

Areas of Interest

Flow induced vascular endothelial cell activation
Flow induced platelet activation and thrombosis
Endothelial cell - platelet interactions in atherosclerosis
Inflammatory responses in atherosclerosis, myocardial infarction and other cardiovascular diseases
Numerical simulation of blood flow field under various disease conditions
Multi-scale modeling of vascular endothelial cells, platelets, leukocytes and erythrocytes interaction

Teaching Interests

Basic Physiology and physiological System Analysis for Engineers
Biomechanics

W. Yin
Wei Yin
Assistant Professor

Oklahoma State University
School of Mechanical and Aerospace Engineering
218 Engineering North
Stillwater, OK 74078-5016
(405) 744-5900
(405) 744-7873 Fax
wei.yin@okstate.edu

Professional Experience

Assistant professor, Mechanical and Aerospace Engineering Department, Oklahoma State University, 2007 - present
Post doctoral research fellow, Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, 2005-2007

Professional Affiliations

American Heart Association member
American society of hematology associate member
New York Academy of Sciences
BMES
Sigma Xi

Select Publications

Yin, W., Venkitachalam, S., Jarrett, E., Staggs,S., Leventis, N., Lu, H., Rubenstein, D.A. Biocompatibility of Polyurea Nanoencapsulated Templated Silica Aerogel. Submitted to Journal of biomedical materials research, July 2008.
 
Rubenstein, D. A. and Yin, W. Glycated albumin modulates platelet susceptibility to flow induced activation and aggregation. Submitted to Journal of Thrombosis and Haemostasis, July, 2008.
 
Peerschke, E.I., Yin, W., Alpert, D.R., Roubey, R.A.S., Salmon, J.E. Serum complement activation on heterologous platelets is associated with arterial thrombosis in patients with systemic lupus erythematosus and antiphospholipid antibodies. Submitted to LUPUS, May, 2008.
 
Yin, W., Czuchlewski, D., Leonard, D. and Peerschke, EIB. Development of proteomic signatures of platelet activation using surface enhanced laser desorption/ionization technology in a clinical setting. American Journal of Clinical Pathology. 2008; 129:862-869.
 
Yin, W., Ghebrehiwet, B., Peerschke, EI. Expression of complement components and inhibitors on platelet microparticles. Platelets, 2008;19:225-233.
 
Yin, W., Ghebrehiwet, B., Weksler, B., Peerschke, EI. Tobacco smoke and shear stress enhance activation of complement component C4 on human endothelial cells. Thrombosis Research. 2008; 122:221-228.
 
Alpert, D., Mandl, L., Erkan, D., Yin, W., Peerschke, E.I., Salmon, J.E. Anti-heparin platelet factor 4 antibodies in systemic lupus erythematosus are associated with IgM antiphospholipid antibodies and the antiphospholipid syndrome. Ann Rheum Dis, 67(3): 395-401, 2008.
 
Peerschke EI, Silver RT, Weksler BB, Yin, W, Bernhardt B, Varon D. Examination of platelet function in whole blood under dynamic flow conditions with the cone and plate(let) analyzer: effect of erythrocytosis and thrombocytosis. Am J Clin Pathol. 2007 Mar; 127(3):1-7.
 
Yin, W., Ghebrehiwet, B., Weksler, B. and Peerschke, E. Direct Classical Pathway Complement Activation on Human Endothelial Cells. Molecular Immunology 2007 Mar; 44(9): 2228-34.
 
Peerschke, E.I.B., Yin, W., Grigg, S.E. and Ghebrehiwet, B. Blood platelets activate the classical pathway of human complement. Journal of thrombosis and Haemostasis, 2006; 4: 2035-42.
 
Yin, W., Krukenkamp, I.B., Gaudette, G, Jesty, J. and Bluestein, D. The thrombogenic performance of a St. Jude Bileaflet MHV in a sheep model. ASAIO Journal, Jan/Feb 2006; 52(1): 28-33.
 
Yin, W., Gallocher, S., Pinchuk, L., Schoephoerster, R., Jesty, J. and Bluestein, D. Flow induced platelet activation in a St. Jude MHV, a trileaflet polymeric heart valve and a St. Jude tissue valve. Artificial Organs, 29(10): 826-31, Oct 2005.
 
Yin, W., Yared, A., Jesty, J., Affeld, K., Bluestein, D. Flow induced platelet activation in bileaflet and monoleaflet mechanical heart valves in a left ventricular assist device. Annals of biomedical eng. 32 :8 :1058-1066, 2004.
 
Bluestein, D., Yin, W., Affeld, K., Jesty, J. Measurements of flow-induced platelet activation in a mechanical heart valve. J. Heart valve disease. 13(3): 501-508, May 2004.
 
Jesty, J., Yin W., Perrotta, P., Bluestein, D. Platelet activation in a circulating flow loop: combined effects of shear stress and exposure time. Platelets, 12: 11-17. 2003.

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